Here's a PBS story with information on how Neanderthal (and Denisovan) genes live on in modern humans. I'm taking it personally; after all, 23andMe tells me that I have more Neanderthal genes than 91% of their customers: Out of the 7,462 variants we tested, we found 279 variants in your DNA that trace back to the Neanderthals. Granted, my Neanderthal ancestry adds up to less than 2% of my DNA, but it's still more than most people have.

So if you think some of my ideas are old-fashioned, even Stone Age, at least I come by them honestly.

The bad news:

In 2020, research by Zeberg and Paabo found that a major genetic risk factor for severe COVID-19 is inherited from Neanderthals. “We compared it to the Neanderthal genome and it was a perfect match,” Zeberg said. “I kind of fell off my chair.”

The good news:

The next year, they found a set of DNA variants along a single chromosome inherited from Neanderthals had the opposite effect: protecting people from severe COVID.

The science behind the news (links in the quotes) is more than I want to think about, and I have no idea how the protective vs. risk factor genes work out in my case. After all, I may have more Neanderthal genes than most, but that's still only a small fraction, and I don't even know if the variants involved are among those tested by 23andMe. So I'll just go back to making my Covid decisions based on other factors.

And smiling when someone suggests my views are out-of-date.

Posted by sursumcorda on Wednesday, November 29, 2023 at 7:23 am | Edit
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